We are on to a terrific slate of Week 6 games in the NFL and we have everything you need, including latest lines, odds, picks, predictions, TV details and those all-important inactives.
We have some fantastic matchups in prospect, including the meeting of the front two in the odds for Super Bowl LVII as Josh Allen and the Buffalo Bills travel to Arrowhead to face Patrick Mahomes and the Kansas City Chiefs.
Then, on Sunday Night Football, the Dallas Cowboys visit the Philadelphia Eagles for a pivotal NFC East matchup between two hated rivals. Excited yet?
We have all the latest lines for you, plus a host of picks and predictions (and some nice signup bonus offers).
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NFL Predictions & Picks for Week 6
We have a ton of picks and predictions for you, and here is how you can get them:
- We have NFL picks against the spread for every single Week 6 game
- Want the best NFL Parlay Picks? Look no further for a same game parlay for TNF.
- If NFL prop bets are your thing, you’ll want to check out these little beauties
- Philadelphia vs Dallas is a mouthwatering matchup on Sunday Night Football and we have picks.
- Jets fan? We have the latest on all the odds for the green half of New York, and picks for that showdown with Aaron Rodgers and the Green Bay Packers.
- Love the Giants? Again we have all the latest odds intel on Big Blue plus picks for a huge test vs Lamar Jackson and the Baltimore Ravens.
- Hi there Dallas Cowboys Nation, we have you covered too with all the latest from the Metroplex, plus some predictions and picks for that trip to the Linc to face the Eagles on SNF.
- And last but absolutely not least, our overall predictions and picks for that Denver Broncos vs Los Angeles Chargers showdown on MNF.
NFL Week 6 Lines, Start Times & TV Details
Here are the very latest lines and spreads heading into the Week 6 schedule:
Week 6
Thursday October 13, 2022
- Washington Commanders (-0.5) at Chicago Bears (+0.5) 8:15 PM Prime Video
Sunday October 16, 2022
- New England Patriots (+2.5) at Cleveland Browns (-2.5) 1:00 PM CBS
- Cincinnati Bengals (-2) at New Orleans Saints (+2) 1:00 PM CBS
- Jacksonville Jaguars (+2) at Indianapolis Colts (-2) 1:00 PM CBS
- San Francisco 49ers (-5.5) at Atlanta Falcons (+5.5) 1:00 PM FOX
- Baltimore Ravens (-6) at New York Giants (+6) 1:00 PM CBS
- Arizona Cardinals (-2.5) at Seattle Seahawks (+2.5) 4:05 PM FOX
- New York Jets (+7) at Green Bay Packers (-7) 1:00 PM FOX
- Minnesota Vikings (-3.5) at Miami Dolphins (+3.5) 1:00 PM FOX
- Tampa Bay Buccaneers (-8) at Pittsburgh Steelers (+8) 1:00 PM FOX
- Carolina Panthers (+10) at Los Angeles Rams (-10) 4:05 PM FOX
- Buffalo Bills (-2.5) at Kansas City Chiefs (+2.5) 4:25 PM CBS
- Dallas Cowboys (+6) at Philadelphia Eagles (-6) 8:20 PM NBC*
Monday October 17, 2022
- Denver Broncos (+5) at Los Angeles Chargers (-5) (Mon) 8:15 PM ESPN
BYE: Detroit Lions, Houston Texans, Las Vegas Raiders, Tennessee Titans
NB: All lines correct on Thursday October 13, 2022
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NFL Week 6 Inactives
If you are betting on the games, you will need these:
Denver Broncos
- WR Jalen Virgil
- CB Darius Phillips
- S Caden Sterns
- S Delarrin Turner-Yell
- ILB Josey Jewell
- TE Albert Okwuegbunam
- DL Eyioma Uwazurik
Los Angeles Chargers
- WR Keenan Allen
- C Corey Linsley
- QB Easton Stick
- RB Isaiah Spiller
- S JT Woods
- DL Christian Covington
- TE Richard Rodgers
Dallas Cowboys
- QB Dak Prescott
- CB Nahshon Wright
- S Markquese Bell
- LB Devin Harper
- T Matt Waletzko
- TE Dalton Schultz
Philadelphia Eagles
- QB Ian Book
- CB Josh Jobe
- S Reed Blankenship
- RB Trey Sermon
- G Josh Sills
- DE Tarron Jackson
Carolina Panthers
- QB Baker Mayfield
- CB Jaycee Horn
- WR Laviska Shenault
- LB Frankie Luvu
- DL Daviyon Nixon
- OL Cade Mays
- DE Amare Barno
Los Angeles Rams
- RB Cam Akers
- QB John Wolford
- CB Cobie Durant
- CB Shaun Jolly
- C Brian Allen
- WR Lance McCutcheon
Arizona Cardinals
- K Matt Prater
- QB Trace McSorley
- C Rodney Hudson
- CB Trayvon Mullen
- RB James Conner
- RB Darrel Williams
- OL Lecitus Smith
Seattle Seahawks
- CB Artie Burns
- WR Penny Hart
- G Gabe Jackson
- DT Al Woods
- S Teez Tabor
Buffalo Bills
- RB Zack Moss
- WR Jake Kumerow
- DT Brandin Bryant
- OL Justin Murray
- LB Baylon Spector
Kansas City Chiefs
- RB Ronald Jones
- S Bryan Cook
- QB Shane Buechele
- CB Rashad Fenton
- DE Joshua Kaindoh
- T Darian Kinnard
- DT Taylor Stallworth
San Francisco 49ers
- DE Nick Bosa
- DL Arik Armstead
- OL Trent Williams
- TE Tyler Kroft
- WR Danny Gray
- DB Jimmie Ward
Atlanta Falcons
- ILB Mykal Walker
- S Erik Harris
- OL Chuma Edoga
- WR Jared Bernhardt
- TE Anthony Firkser
- OLB Ade Ogundeji
New England Patriots
- QB Mac Jones
- WR Nelson Agholor
- CB Jonathan Jones
- RB Damien Harris
- LB Josh Uche
- DT Lawrence Guy
- FS Joshuah Bledsoe
Cleveland Browns
- QB Kellen Mond
- CB Denzel Ward
- RB Demetric Felton Jr.
- T Joe Haeg
- G Drew Forbes
- T Chris Hubbard
- DE Jadeveon Clowney
New York Jets
- QB Mike White
- TE Jeremy Ruckert
- S Tony Adams
- OL Mike Remmers
- WR Denzel Mims
- CB Bryce Hall
Green Bay Packers
- WR Christian Watson
- OL Rasheed Walker
- OL Sean Rhyan
- WR Samori Toure
- DL Jonathan Ford
Jacksonville Jaguars
- WR Marvin Jones Jr.
- RB Snoop Conner
- S Tyree Gillespie
- CB Montaric Brown
- OLB De’Shaan Dixon
- DL Folorunso Fatukasi
Indianapolis Colts
- QB Nick Foles
- C Wesley French
- RB Nyheim Hines
- DT Eric Johnson II
- LB Shaquille Leonard
- DE Kwity Paye
- RB Jonathan Taylor
Minnesota Vikings
- S Theo Jackson
- G/C Chris Reed
- OT Vederian Lowe
- DL Esezi Otomewo
- DL Khyiris Tonga
- OLB D.J. Wonnum
Miami Dolphins
- QB Tua Tagovailoa
- RB Myles Gaskin
- WR Erik Ezukanma
- CB Kader Kohou
- OT Terron Armstead
- DT John Jenkins
- TE Durham Smythe
Cincinnati Bengals
- CB Cam-Taylor Britt
- HB Trayveon Williams
- OT D’Ante Smtih
- G Jackson Carman
New Orleans Saints
- WR Jarvis Landry
- CB Marshon Lattimore
- WR Chris Olave
- WR Michael Thomas
- OL Calvin Throckmorton
- DE Payton Turner
- TE Nick Vannett
Baltimore Ravens
- WR Rashod Bateman
- G Ben Cleveland
- OLB Justin Houston
- CB Jalyn Armour-Davis
- RB Justice Hill
New York Giants
- CB Cor’Dale Flott
- WR Kenny Golladay
- S Jason Pinnock
- WR Kadarius Toney
- OLB Azeez Ojulari
Tampa Bay Buccaneers
- QB Kyle Trask
- WR Julio Jones
- TE Kyle Rudolph
- CB Sean Murphy-Bunting
- S Logan Ryan
- S Mike Edwards
- DL Akiem Hicks
Pittsburgh Steelers
- QB Mason Rudolph
- CB Cam Sutton
- CB Ahkello Witherspoon
- CB Levi Wallace
- S Minkah Fitzpatrick
- G Kendrick Green
- TE Pat Freiermuth